Fecal Microbiome Transplant Clinical Trials

Below is a list of fecal microbiota transplantation (FMT) clinical trials we have identified. Many of these studies focus on patients with advanced or treatment-resistant cancer, but eligibility requirements vary and a listed trial may not be appropriate, available, or currently enrolling for your specific situation.

This information is provided for educational purposes only and is not medical advice, a treatment recommendation, or a guarantee of eligibility. FMT is still investigational for cancer and may carry serious risks. Do not attempt FMT outside a properly supervised clinical trial or medical setting. Trial information and enrollment status may change, so please confirm all details directly with the study team and discuss any potential option with your treating oncologist. Please note: Some of these studies are conducted outside the U.S. and may require international travel.

RECRUITING TRIALS (as of July 2026)

• NCT04935684‍

  • CONDITION: Acute Leukemia in Remission | Myelodysplastic Syndromes | Myeloproliferative Syndrome | Hodgkin Lymphoma | Lymphoma, Non-Hodgkin | Myeloma | Chronic Lymphocytic Leukemia ‍

• NCT05251389‍

  • CONDITION: Melanoma Stage III | Melanoma Stage IV ‍

• NCT05502913‍

  • CONDITION: Metastatic Lung Cancer ‍

• NCT05690048‍

  • CONDITION: Immunotherapy | HCC - Hepatocellular Carcinoma ‍

• NCT05669846‍

  • CONDITION: Non Small Cell Lung Cancer ‍

• NCT06218602‍

  • CONDITION: Lymphoma ‍

• NCT07042438‍

  • CONDITION: Recurrent Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma ‍

• NCT06623461‍ ‍

  • CONDITION: Melanoma ‍ ‍

• NCT06355583

  • CONDITION: Acute Lymphoblastic Leukaemia | Acute Leukemia of Ambiguous Lineage | Chronic Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Acute Myeloid Leukemia

ACTIVE /NOT RECRUITING TRIALS (as of July 2026) ‍ ‍

• NCT03686202

  • CONDITION: All Solid Tumors

• NCT05286294

  • CONDITION: Melanoma Stage IV| Head and Neck Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-High | Clear Cell Renal Cell Carcinoma | Non-small Cell Lung Cancer

• NCT04729322

  • CONDITION: Metastatic Colorectal Adenocarcinoma | Metastatic Small Intestinal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IV Small Intestinal Adenocarcinoma AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8

• NCT04951583

  • CONDITION: Non Small Cell Lung Cancer Metastatic | Advanced Melanoma